Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360600 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL193513 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL1203937 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL132349 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL30953203 | 0.90 | MME (0.41) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL8058978 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| Ammonia Solution, Strong SCHEMBL10483779 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL7105559 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| Ammonia Solution, Strong SCHEMBL10483782 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MMELMNAGAA | |
| SCHEMBL25412479 | 0.85 | MME (0.43) | SMN1; SMN2ALDH1A1MMELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876329-B1 | PROCESS FOR THE PRODUCTION OF N-ACETYL-D,L-ALPHA-AMINOCARBOXYLIC ACIDS | DEGUSSA (DE) | 2001-07-18 | — | — | EP | disclosed |
| EP-0874801-B1 | PROCESS FOR OBTAINING OPTICALLY ACTIVE L-ALPHA-AMINOCARBOXYLIC ACIDS FROM CORRESPONDING RACEMIC D,L-ALPHA-AMINOCARBOXYLIC ACIDS | DEGUSSA (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-6114163-A | ACETYLATING RACEMIC MIXTURE, NEUTRALIZING SOLUTION, DEACETYLING USING STEREOSPECIFIC ACYLASE TO PRODUCE L-STEREOISOMERS, SEPARATING OUT WANTED PRODUCT, ADJUSTING SOLUTION, RACEMIZING MIXTURE, AND DEACETYLATING AGAIN | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |