Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766402 | 1.00 | MEN1 (0.43) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7766325 | 0.89 | MEN1 (0.38) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7766334 | 0.89 | MEN1 (0.38) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7763012 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7763018 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7763022 | 0.88 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL3087169 | 0.82 | KMT2A (0.53) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2455165 | 0.82 | KMT2A (0.53) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL10553387 | 0.82 | KMT2A (0.53) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL3359352 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854875-B1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6159961-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| US-5958914-A | FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0854875-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997012890-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-10 | — | — | WO | disclosed |