SCHEMBL776643

SCHEMBL776643

Cc1ccccc1OP(C)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
MAPT P10636 1/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
NOTUM Q6P988 1/20 0.41
INPPL1 O15357 1/20 0.41
INPP5B P32019 1/20 0.41
INPP5A Q14642 1/20 0.41
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
SRC P12931 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
USP2 O75604 1/20 0.40
PDE3A Q14432 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540057 1.00 KDM4E (0.46) KDM4EMAPTCYP2C19CYP1A2CYP3A4
SCHEMBL1100136 0.85 INPPL1 (0.57) KDM4EMAPTCYP2C19CYP1A2CYP3A4
SCHEMBL497602 0.85 KDM4E (0.47) KDM4EMAPTCYP2C19CYP1A2CYP3A4
SCHEMBL4119537 0.84 MAPT (0.65) MAPTCYP2C19CYP1A2CYP3A4INPPL1
O-Xylene SCHEMBL29031713 0.83 INPPL1 (0.55) KDM4EMAPTCYP2C19CYP1A2CYP3A4
SCHEMBL29199066 0.83 INPPL1 (0.55) KDM4EMAPTCYP2C19CYP1A2CYP3A4
Phosphine SCHEMBL28157684 0.83 INPPL1 (0.55) KDM4EMAPTCYP2C19CYP1A2CYP3A4
Fluoride SCHEMBL31047191 0.83 KDM4E (0.46) KDM4EMAPTCYP2C19CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL11749404 0.83 INPPL1 (0.55) KDM4EMAPTCYP2C19CYP1A2CYP3A4
Ammonia Solution, Strong SCHEMBL17670023 0.83 INPPL1 (0.55) KDM4EMAPTCYP2C19CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500614-B1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEM CO (US) 2025-08-06 EP disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-11447601-B2 Polyester compositions which comprise tetramethylcyclobutanediol and ethylene glycol for calendering EASTMAN CHEMICAL COMPANY (US) 2022-09-20 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-20190211145-A1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2019-07-11 US disclosed
EP-3500614-A1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING Eastman Chemical Company (US) 2019-06-26 EP disclosed
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
US-20050154114-A1 Compatibilized blends of biodegradable polymers with improved rheology NOVAMONT SPA (IT) 2005-07-14 US disclosed
WO-2005063883-A1 POLYMER BLENDS WITH IMPROVED RHEOLOGY AND IMPROVED UNNOTCHED IMPACT STRENGTH EASTMAN CHEMICAL COMPANY (US) 2005-07-14 WO disclosed
WO-2005063881-A1 POLYMER BLENDS WITH IMPROVED NOTCHED IMPACT STRENGTH EASTMAN CHEMICAL COMPANY (US) 2005-07-14 WO disclosed
US-20050137332-A1 Polymer blends with improved notched impact strength NOVAMONT SPA (IT) 2005-06-23 US disclosed
US-20050137304-A1 Process for calendering of polyesters STRAND MARC A (US) 2005-06-23 US disclosed
US-20050137356-A1 Polymer blends with improved rheology and improved unnotched impact strength NOVAMONT SPA (IT) 2005-06-23 US disclosed
WO-2005054354-A1 POLYESTER COMPOSITIONS FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2005-06-16 WO disclosed
US-20050113556-A1 with a proper balance of inherent viscosity and branching provide superior processing characteristics during calendering EASTMAN CHEMICAL COMPANY 2005-05-26 US disclosed
WO-2004060990-A2 FLAME RETARDANT POLYESTER COMPOSITIONS FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2004-07-22 WO disclosed
US-20040127609-A1 Flame retardant polyester compositions for calendering EASTMAN CHEMICAL COMPANY 2004-07-01 US disclosed