Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766717 | 1.00 | KDM4E (0.55) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL14906259 | 0.87 | BCHE (0.59) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL7201041 | 0.87 | KDM4E (0.61) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL27763762 | 0.83 | ACE (0.57) | CCKBR | |
| SCHEMBL30735894 | 0.79 | KDM4E (0.64) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL3855611 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL3855614 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL29212821 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL9960361 | 0.79 | KMT2A (0.60) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL11179965 | 0.79 | KDM4E (0.54) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001088178-A2 | PEPTIDE SUBSTRATES FOR DIRECT MEASURING OF ENZYME ACTIVITIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2001-11-22 | — | — | WO | claimed |
| WO-2001088178-A2 | PEPTIDE SUBSTRATES FOR DIRECT MEASURING OF ENZYME ACTIVITIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2001-11-22 | — | — | WO | disclosed |