Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766733 | 1.00 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8596445 | 0.85 | IRAK4 (0.39) | IRAK4KDM4ECYP3A4USP2CYP1A2 | |
| SCHEMBL8596448 | 0.85 | IRAK4 (0.39) | IRAK4KDM4ECYP3A4USP2CYP1A2 | |
| SCHEMBL8593882 | 0.84 | IRAK4 (0.36) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8593884 | 0.84 | IRAK4 (0.36) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8120612 | 0.84 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8692339 | 0.84 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8692336 | 0.84 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL8598284 | 0.84 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA | |
| SCHEMBL7198151 | 0.84 | IRAK4 (0.37) | IRAK4KDM4ECYP3A4USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100785-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | Aventis CropScience GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-6197729-B1 | COMBATING PEST WHICH COMPRISES APPLYING TO PEST OR ITS LOCUS PESTICIDAL CYCLOHEXYLAMINOPYRIMIDINNE COMPOUND | HOECHST SCHERING AGREVO (DE) | 2001-03-06 | — | — | US | disclosed |
| WO-2000007998-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |