Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148146 | 0.82 | AOC3 (0.61) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL7130084 | 0.82 | AOC3 (0.61) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL5187903 | 0.80 | AOC3 (0.64) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL19148406 | 0.80 | AOC3 (0.59) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL17295895 | 0.80 | AOC3 (0.59) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL13537066 | 0.79 | MAPK1 (0.49) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL22776083 | 0.78 | AOC3 (0.57) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL7710668 | 0.78 | AOC3 (0.57) | AOC3KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28609252 | 0.77 | AOC3 (0.56) | AOC3KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL13067533 | 0.77 | CA1 (0.50) | AOC3ALDH1A1LMNAALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001226-B | Tricyclic heterocyclic compounds and JAK inhibitor | 日产化学工业株式会社 | 2017-09-08 | — | — | CN | disclosed |
| EP-1100785-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | Aventis CropScience GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007998-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |