SCHEMBL7766832

SCHEMBL7766832

C=C(C)C(=O)Oc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.64
FFAR1 O14842 7/20 0.51
KMT2A Q03164 3/20 0.48
ATM Q13315 1/20 0.48
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
POLB P06746 2/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ACACB O00763 1/20 0.41
HAO1 Q9UJM8 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NLRP3 Q96P20 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766154 0.93 ELANE (0.57) ELANEFFAR1KMT2AATMPOLB
SCHEMBL16182736 0.93 ELANE (0.57) ELANEFFAR1KMT2AATMPOLB
SCHEMBL16182693 0.93 ELANE (0.57) ELANEFFAR1KMT2AATMPOLB
SCHEMBL16182916 0.88 ELANE (0.50) ELANEFFAR1KMT2AATMACACB
SCHEMBL16182872 0.86 ELANE (0.52) ELANEFFAR1KMT2AATMACACB
SCHEMBL17370256 0.84 ELANE (0.50) ELANEFFAR1KMT2AATMPOLB
SCHEMBL17370257 0.84 ELANE (0.49) ELANEFFAR1KMT2AATMPOLB
SCHEMBL16182711 0.84 ELANE (0.49) ELANEFFAR1KMT2AATMPOLB
SCHEMBL16182804 0.84 ACACB (0.48) ELANEFFAR1ACACB
SCHEMBL17370464 0.84 ELANE (0.49) ELANEFFAR1KMT2AATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563403-B1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORP (JP) 2001-05-30 EP disclosed
US-5769393-A Liquid crystal elements and method of producing same SEIKO EPSON CORPORATION (JP) 1998-06-23 US disclosed
EP-0563403-A1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORPORATION (JP) 1993-10-06 EP disclosed