SCHEMBL7766882

SCHEMBL7766882

CC(=O)OC1CCC(C2CCC(C3CCC(=O)CC3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CHRM2 P08172 6/20 0.34
CHRM1 P11229 4/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADORA2A P29274 1/20 0.32
CHRM4 P08173 3/20 0.32
CHRM3 P20309 3/20 0.32
CHRM5 P08912 2/20 0.32
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1207769 0.88 POLB (0.38) ALDH1A1TP53MAPTMAPK1CHRM2
SCHEMBL25500893 0.85 CHRM2 (0.42) ALDH1A1CHRM2CHRM1MEN1CYP2D6
SCHEMBL11316954 0.85 CHRM2 (0.39) ALDH1A1TP53MAPTMAPK1CHRM2
SCHEMBL12476221 0.78 CHRM2 (0.42) ALDH1A1CHRM2CHRM1MEN1CYP2D6
SCHEMBL177205 0.78
SCHEMBL12158777 0.78 CHRM2 (0.37) ALDH1A1CHRM2CHRM1MEN1CYP2D6
SCHEMBL14877968 0.78 CYP19A1 (0.40) ALDH1A1MAPTCHRM2CHRM1MEN1
SCHEMBL9687419 0.77 TRIM24 (0.42) ALDH1A1KMT2ACYP2C19
SCHEMBL28780475 0.76
Ammonia Solution, Strong SCHEMBL28770241 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747336-B1 Alkenyl cyclohexane derivatives and liquid crystal compositions CHISSO CORP (JP) 2001-07-25 EP disclosed
US-5709820-A MIXTURES CHISSO CORPORATION (JP) 1998-01-20 US disclosed
EP-0747336-A1 Alkenyl cyclohexane derivatives and liquid crystal compositions Chisso Corporation (JP) 1996-12-11 EP disclosed