SCHEMBL7768074

SCHEMBL7768074

CCCCCCCC(S)[Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.36
LMNA P02545 2/20 0.35
DNM1 Q05193 2/20 0.34
SMPD1 P17405 3/20 0.33
OPRM1 P35372 1/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
FDPS P14324 3/20 0.32
GPR84 Q9NQS5 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28505438 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL3688687 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL20576622 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL11783477 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL2979460 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL989249 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL10324721 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL19410710 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL28419902 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL2985541 0.81 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824113-B2 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2012-06-27 EP disclosed
EP-0824113-B1 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2001-06-20 EP disclosed
EP-0824113-A1 Supported catalyst, process for its preparation and its use in olefin polymerization HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-18 EP disclosed
EP-0811640-A1 Supported catalyst system, process for its preparation and its use in the polymerization of olefins HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-10 EP disclosed