Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773967 | 0.88 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL7768160 | 0.87 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL6174701 | 0.87 | F2 (0.83) | F2ESR1ESR2 | |
| SCHEMBL7444869 | 0.86 | F2 (0.75) | F2ESR1ESR2 | |
| SCHEMBL8004396 | 0.85 | F2 (0.74) | F2KDM4ESMN1; SMN2TP53 | |
| SCHEMBL6597667 | 0.84 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL6597655 | 0.84 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL7989752 | 0.84 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL7989747 | 0.84 | F2 (0.81) | F2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL6595703 | 0.84 | F2 (0.80) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |