Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597094 | 0.91 | ESR1 (0.72) | ESR1ESR2F2UBE2N | |
| SCHEMBL6596715 | 0.90 | ESR1 (0.60) | ESR1ESR2F2 | |
| SCHEMBL7775991 | 0.89 | ESR1 (0.55) | ESR1ESR2F2 | |
| SCHEMBL6592800 | 0.89 | ESR1 (0.82) | ESR1ESR2F2UBE2N | |
| SCHEMBL7774305 | 0.87 | ESR1 (0.79) | ESR1ESR2UBE2N | |
| SCHEMBL6593201 | 0.87 | ESR1 (0.68) | ESR1ESR2F2 | |
| SCHEMBL11547737 | 0.87 | ESR1 (0.83) | ESR1ESR2F2UBE2N | |
| SCHEMBL6596227 | 0.87 | ESR1 (0.83) | ESR1ESR2F2UBE2N | |
| SCHEMBL7414713 | 0.86 | ESR1 (0.73) | ESR1ESR2F2 | |
| SCHEMBL6596053 | 0.86 | ESR1 (0.79) | ESR1ESR2F2UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |