SCHEMBL7769145

SCHEMBL7769145

[CH2]CC(=O)CCC(=O)CCC(=O)CCC(=O)CC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 4/20 0.33
FFAR3 O14843 3/20 0.33
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
IAPP P10997 2/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788651 1.00 TDP1 (0.47) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL8061372 0.97 TDP1 (0.50) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL27570895 0.86 TDP1 (0.45) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL30255411 0.85 TDP1 (0.64) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL8371300 0.85 TDP1 (0.64) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL8984748 0.85 TDP1 (0.64) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL13379743 0.85 TDP1 (0.64) TDP1ALDH1A1FFAR3HDAC3HDAC1
SCHEMBL27554524 0.83 TDP1 (0.47) TDP1ALDH1A1FFAR3NPC1RAB9A
SCHEMBL127111 0.82
SCHEMBL619312 0.82 TDP1 (0.69) TDP1ALDH1A1FFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752461-B1 Composition and use of reducing combustion chamber deposits CHEVRON CHEM CO (US) 2001-09-19 EP disclosed
US-6136051-A FUEL COMPRISING HYDROCARBONS BOILING IN GASOLINE RANGE; A POLYALKYLENE-AMINE ENDCAPPED POLYISOBUTYLENE DETERGENT; AND A MINERAL OIL CARRIER; OPERATING INTERNAL COMBUSTION ENGINE WITH FUEL TO CONTROL COMBUSTION CHAMBER DEPOSITS CHEVRON CHEMICAL COMPANY (US) 2000-10-24 US disclosed
US-5652201-A INCLUDING OIL-SOLUBLE OVERBASED ALKALINE EARTH METAL-CONTAINING SULFONATE DETERGENT, BORON-FREE ADDITIVE FORMED BY HEATING ASHLESS DISPERSANT CONTAINING BASIC NITROGEN AND/OR HYDROXYL GROUP WITH INORGANIC PHOSPHORUS ACID ETHYL PETROLEUM ADDITIVES INC. (US) 1997-07-29 US disclosed
EP-0752461-A1 Method and composition for reduction of combustion chamber deposits CHEVRON CHEMICAL COMPANY (US) 1997-01-08 EP disclosed
EP-0492934-B1 Lubricating oil compositions and concentrates and the use thereof ETHYL PETROLEUM ADDITIVES INC (US) 1994-08-10 EP disclosed
EP-0516461-A1 Lubricating oil compositions and concentrates and the use thereof ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-12-02 EP disclosed
EP-0493928-A1 Lubricating oil compositions, concentrates and the use thereof ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-07-08 EP disclosed
EP-0492934-A1 Lubricating oil compositions and concentrates and the use thereof ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-07-01 EP disclosed