Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771325 | 0.92 | CYP1A2 (0.46) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7769840 | 0.91 | SLC29A1 (0.45) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7771342 | 0.90 | CYP1A2 (0.46) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7773554 | 0.89 | SLC29A1 (0.46) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7771314 | 0.88 | SLC29A1 (0.46) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7124742 | 0.87 | CYP3A4 (0.51) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7773524 | 0.85 | SLC29A1 (0.41) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7131221 | 0.85 | CYP1A2 (0.40) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7126375 | 0.85 | CYP1A2 (0.40) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A | |
| SCHEMBL7773551 | 0.84 | CYP1A2 (0.49) | CYP1A2SLC29A1CYP2C19CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785208-B1 | Phosphonate nucleotide compounds | MITSUBISHI CHEM CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |