Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776272 | 0.84 | PTPN1 (0.45) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL28656982 | 0.69 | PTPN1 (0.89) | PTPN1HPGDKMT2AMEN1LMNA | |
| SCHEMBL1946708 | 0.69 | NPSR1 (0.72) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL125695 | 0.69 | PTPN1 (0.89) | PTPN1HPGDKMT2AMEN1LMNA | |
| SCHEMBL23946044 | 0.68 | PTPN1 (0.49) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL1948869 | 0.66 | NPSR1 (0.75) | PTPN1HPGDKMT2AMEN1LMNA | |
| SCHEMBL28258088 | 0.66 | CETP (0.77) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL28256535 | 0.66 | CETP (0.77) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL12323604 | 0.66 | CETP (0.77) | PTPN1HPGDKMT2AMEN1TSHR | |
| SCHEMBL2246735 | 0.66 | MEN1 (0.96) | PTPN1HPGDKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |