Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 13/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 7/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPRE | P23469 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861357 | 0.84 | IDO1 (0.66) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL4860619 | 0.80 | IDO1 (0.60) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL5678007 | 0.77 | IDO1 (0.70) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL5676416 | 0.76 | IDO1 (0.62) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL6035697 | 0.76 | IDO1 (0.56) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL4855512 | 0.75 | IDO1 (0.61) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL7625953 | 0.74 | IDO1 (0.54) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL5677981 | 0.73 | IDO1 (0.61) | IDO1MEN1KMT2ATDP1 | |
| SCHEMBL6035263 | 0.73 | IDO1 (0.65) | IDO1MAP2K1MAP2K2PTPRCPTPN2 | |
| SCHEMBL6035920 | 0.73 | MAP2K1 (0.55) | IDO1MAP2K1MAP2K2PTPRCPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001055376-A | DIARYL AMINE | WARNER LAMBERT CO | 2001-02-27 | — | — | JP | disclosed |