Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769644 | 1.00 | RARB (0.39) | RARBCYP3A4CYP2C9P2RY14SPHK1 | |
| SCHEMBL7769671 | 0.90 | RARB (0.42) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7769674 | 0.90 | RARB (0.42) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL8397579 | 0.90 | RARB (0.43) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL8397581 | 0.90 | RARB (0.43) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7773901 | 0.88 | RARB (0.40) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7766357 | 0.88 | RARB (0.40) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7773902 | 0.88 | RARB (0.40) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7766351 | 0.88 | RARB (0.40) | RARBCYP3A4CYP2C9SPHK1APP | |
| SCHEMBL7773877 | 0.88 | GRM2 (0.40) | RARBCYP3A4CYP2C9SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676402-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5578244-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |