Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848521 | 0.91 | NSD2 (0.45) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL3189588 | 0.87 | KDM4E (0.45) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL15300823 | 0.85 | KDM4E (0.44) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL1824099 | 0.85 | NSD2 (0.46) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL4311584 | 0.85 | HTR2A (0.39) | NSD2NSD3HTR2AHTR2CHTR2B | |
| SCHEMBL15677337 | 0.84 | KDM4E (0.42) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL10458198 | 0.84 | PDE10A (0.41) | KDM4EHTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL5881114 | 0.83 | HPGD (0.55) | NSD2NSD3KDM4EPOLBAAK1 | |
| SCHEMBL1821512 | 0.83 | NSD2 (0.45) | NSD2NSD3KDM4EPOLBPKM | |
| SCHEMBL27738395 | 0.83 | NSD2 (0.45) | NSD2NSD3KDM4EPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109423298-B | Novel dibenzothiophene liquid crystal compound and preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | LIFE MOLECULAR IMAGING LIMITED (GB) | 2017-01-05 | — | — | US | disclosed |
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | LIFE MOLECULAR IMAGING LIMITED (GB) | 2017-01-05 | — | — | US | disclosed |
| WO-2015110263-A1 | CARBAZOLE AND CARBOLINE COMPOUNDS FOR USE IN THE DIAGNOSIS, TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH AMYLOID OR AMYOLID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2015-07-30 | — | — | WO | disclosed |
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002005-A1 | Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins | APP, BACE1, PSEN1 | NSD2 3006/4885NSD3 1773/4885KDM4E 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.