Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770231 | 1.00 | S1PR1 (0.40) | S1PR1S1PR3FFAR4RARBC3AR1 | |
| SCHEMBL7771011 | 0.95 | FFAR4 (0.40) | S1PR1S1PR3FFAR4RARBC3AR1 | |
| SCHEMBL7771013 | 0.95 | FFAR4 (0.40) | S1PR1S1PR3FFAR4RARBC3AR1 | |
| SCHEMBL8440137 | 0.88 | FFAR4 (0.39) | FFAR4RARBRARAKMT2ALMNA | |
| SCHEMBL8440138 | 0.88 | FFAR4 (0.39) | FFAR4RARBRARAKMT2ALMNA | |
| SCHEMBL7769674 | 0.88 | RARB (0.42) | FFAR4RARBCYP3A4SPHK1 | |
| SCHEMBL7769671 | 0.88 | RARB (0.42) | FFAR4RARBCYP3A4SPHK1 | |
| SCHEMBL8397581 | 0.88 | RARB (0.43) | RARBCYP3A4SPHK1 | |
| SCHEMBL8397579 | 0.88 | RARB (0.43) | RARBCYP3A4SPHK1 | |
| SCHEMBL7773877 | 0.88 | GRM2 (0.40) | S1PR1S1PR3FFAR4RARBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676402-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |