Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770254 | 1.00 | KDM1A (0.33) | KDM1AS1PR1S1PR3RARBFFAR4 | |
| SCHEMBL7770283 | 0.94 | CYP17A1 (0.33) | S1PR1RARBGPR84 | |
| SCHEMBL7770281 | 0.94 | CYP17A1 (0.33) | S1PR1RARBGPR84 | |
| SCHEMBL7766408 | 0.84 | RARB (0.39) | S1PR1S1PR3RARBGPR84 | |
| SCHEMBL7766403 | 0.84 | RARB (0.39) | S1PR1S1PR3RARBGPR84 | |
| SCHEMBL7766398 | 0.82 | RARB (0.33) | RARB | |
| SCHEMBL7766401 | 0.82 | RARB (0.33) | RARB | |
| SCHEMBL7769643 | 0.82 | KDM1A (0.33) | KDM1AS1PR1S1PR3RARBFFAR4 | |
| SCHEMBL7771561 | 0.82 | KDM1A (0.36) | KDM1AFFAR4 | |
| SCHEMBL7771562 | 0.82 | KDM1A (0.36) | KDM1AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676402-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5578244-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |