Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.70 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169558 | 1.00 | TDP1 (0.70) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481589 | 0.89 | TDP1 (0.72) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481568 | 0.89 | TDP1 (0.72) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9482446 | 0.87 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9482431 | 0.87 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7766669 | 0.85 | TDP1 (0.52) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7766665 | 0.85 | TDP1 (0.52) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481007 | 0.84 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481004 | 0.84 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9482639 | 0.84 | TDP1 (0.52) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854875-B1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6159961-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |