Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770646 | 1.00 | GRM2 (0.45) | GRM2RARBFFAR4S1PR3S1PR1 | |
| SCHEMBL9358110 | 0.92 | GRM2 (0.47) | GRM2RARBFFAR4S1PR3S1PR1 | |
| SCHEMBL9358114 | 0.92 | GRM2 (0.47) | GRM2RARBFFAR4S1PR3S1PR1 | |
| SCHEMBL3160085 | 0.92 | GRM2 (0.42) | GRM2RARBFFAR4S1PR3S1PR1 | |
| SCHEMBL3160080 | 0.92 | GRM2 (0.42) | GRM2RARBFFAR4S1PR3S1PR1 | |
| SCHEMBL8902633 | 0.89 | RARB (0.44) | GRM2RARBS1PR3S1PR1CYP3A4 | |
| SCHEMBL8902637 | 0.89 | RARB (0.44) | GRM2RARBS1PR3S1PR1CYP3A4 | |
| SCHEMBL8034576 | 0.87 | GRM2 (0.46) | GRM2FFAR4MMP12MOGAT2CTSD | |
| SCHEMBL9656565 | 0.87 | JAK2 (0.36) | GRM2FFAR4MMP12MOGAT2TSHR | |
| SCHEMBL9656560 | 0.87 | JAK2 (0.36) | GRM2FFAR4MMP12MOGAT2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700983-B1 | Electrooptical liquid crystal system | MERCK PATENT GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0511487-B1 | Electro-optical liquid crystal system | MERCK PATENT GMBH (DE) | 1996-05-29 | — | — | EP | disclosed |
| EP-0700983-A2 | Electrooptical liquid crystal system | MERCK PATENT GmbH (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0511487-A1 | Electro-optical liquid crystal system | MERCK PATENT GmbH (DE) | 1992-11-04 | — | — | EP | disclosed |