SCHEMBL7770649

SCHEMBL7770649

CCCC1CCC(CCc2ccc(-c3ccc(Cl)cc3)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.49
FAAH O00519 1/20 0.42
MAOA P21397 1/20 0.42
GPR84 Q9NQS5 1/20 0.40
SLC6A3 Q01959 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
HRH1 P35367 1/20 0.38
HTR2B P41595 1/20 0.38
CHRNA4 P43681 1/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770647 1.00 MAOB (0.49) MAOBFAAHMAOAGPR84SLC6A3
SCHEMBL10381925 0.95 MAOB (0.53) MAOBFAAHMAOASLC6A3L3MBTL1
SCHEMBL9133245 0.95 MAOB (0.53) MAOBFAAHMAOASLC6A3L3MBTL1
SCHEMBL8456020 0.93 MAOB (0.49) MAOBFAAHMAOAGPR84SLC6A3
SCHEMBL8456015 0.93 MAOB (0.49) MAOBFAAHMAOAGPR84SLC6A3
SCHEMBL10899249 0.91 MAOB (0.47) MAOBMAOAGPR84
SCHEMBL10899256 0.91 MAOB (0.47) MAOBMAOAGPR84
SCHEMBL8448627 0.90 MAOB (0.47) MAOBFAAHMAOASLC6A3HTR2A
SCHEMBL8448631 0.90 MAOB (0.47) MAOBFAAHMAOASLC6A3HTR2A
SCHEMBL8414794 0.90 MAOB (0.49) MAOBFAAHMAOASLC6A3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700983-B1 Electrooptical liquid crystal system MERCK PATENT GMBH (DE) 2001-07-11 EP disclosed
EP-0511487-B1 Electro-optical liquid crystal system MERCK PATENT GMBH (DE) 1996-05-29 EP disclosed
EP-0700983-A2 Electrooptical liquid crystal system MERCK PATENT GmbH (DE) 1996-03-13 EP disclosed
EP-0511487-A1 Electro-optical liquid crystal system MERCK PATENT GmbH (DE) 1992-11-04 EP disclosed