Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770742 | 0.88 | CYP3A4 (0.46) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7768662 | 0.87 | CYP3A4 (0.46) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7770189 | 0.86 | HDAC3 (0.42) | CYP3A4EGFRKMT2AHTTSMN1; SMN2 | |
| SCHEMBL7765136 | 0.85 | CYP3A4 (0.43) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7768661 | 0.85 | CYP3A4 (0.46) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7770722 | 0.84 | CYP3A4 (0.42) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL1463877 | 0.84 | EGFR (0.55) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7768664 | 0.83 | CYP3A4 (0.45) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL7765138 | 0.82 | CYP3A4 (0.44) | CYP3A4EGFRKMT2AKDM4EHTT | |
| SCHEMBL8922268 | 0.81 | CYP3A4 (0.49) | CYP3A4EGFRKMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749974-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2001-06-27 | — | — | EP | claimed |
| CN-1066739-C | Phosphonic diester deriv | OTSUKA PHARMA CO LTD (JP) | 2001-06-06 | — | — | CN | disclosed |
| CN-1147257-A | Phosphonic diester deriv | OTSUKA PHARMA CO LTD (JP) | 1997-04-09 | — | — | CN | disclosed |