Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352210 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL23670799 | 1.00 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL7771634 | 0.89 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL7773656 | 0.89 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL27716385 | 0.82 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL7771608 | 0.78 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28563976 | 0.78 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26080088 | 0.77 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3BCHE | |
| SCHEMBL7357964 | 0.76 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7351976 | 0.75 | SLC18A3 (0.41) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |