Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.66 |
| ▸ | ESR1 | P03372 | 5/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.66 |
| ▸ | PPARA | Q07869 | 2/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321328 | 0.89 | GAA (0.82) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL11485988 | 0.87 | PPARA (0.83) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL4561660 | 0.87 | GAA (0.79) | GAAPPARALMNAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL8444293 | 0.87 | PPARA (0.68) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL20806916 | 0.86 | CYP19A1 (0.66) | GAACYP19A1ESR1ESR2LMNA | |
| SCHEMBL14366324 | 0.85 | GAA (0.77) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL2127341 | 0.85 | PPARA (0.81) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL20624042 | 0.85 | PPARA (0.81) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL6652325 | 0.85 | PPARA (0.81) | GAAPPARALMNAL3MBTL1MAPT | |
| SCHEMBL7114335 | 0.85 | PPARA (0.81) | GAAPPARALMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004334-B1 | CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-21 | — | — | EP | claimed |
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |
| EP-0693488-B1 | An improved process for preparing 3-(4-aminoethoxy-benzoyl)benzo beta -thiophenes | LILLY CO ELI (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0693488-A1 | An improved process for preparing 3-(4-aminoethoxy-benzoyl)benzo beta -thiophenes | ELI LILLY AND COMPANY (US) | 1996-01-24 | — | — | EP | disclosed |
| US-4585693-A | Polymer-bound ultraviolet stabilizer coating compositions containing cross linkers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4495325-A | Polymer-bound ultraviolet stabilizer coating compositions containing cross linkers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| US-4215139-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | disclosed |