Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773516 | 1.00 | CA1 (0.52) | CA1CA9LMNACYP2C9ALDH1A1 | |
| SCHEMBL18268915 | 0.83 | CA1 (0.50) | CA1CA9LMNACYP2C9ALDH1A1 | |
| SCHEMBL111476 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL7857216 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL273031 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL24983738 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| Tetrahydrofuran SCHEMBL20339203 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL114946 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL30489732 | 0.80 | CA1 (0.80) | CA1CA9LMNAALDH1A1TP53 | |
| SCHEMBL11666040 | 0.78 | CA1 (0.68) | CA1CA9LMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884315-B1 | Dioxacycloalkan-8-ones | GIVAUDAN SA (CH) | 2001-09-19 | — | — | EP | claimed |
| US-5948812-A | ORDORANTS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 1999-09-07 | — | — | US | claimed |
| EP-0884315-A1 | Dioxacycloalkan-8-ones | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-16 | — | — | EP | claimed |
| EP-0884315-B1 | Dioxacycloalkan-8-ones | GIVAUDAN SA (CH) | 2001-09-19 | — | — | EP | disclosed |
| US-5948812-A | ORDORANTS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 1999-09-07 | — | — | US | disclosed |
| EP-0884315-A1 | Dioxacycloalkan-8-ones | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-16 | — | — | EP | disclosed |