SCHEMBL7774103

SCHEMBL7774103

CCCCOC(Cc1ccc(OCCCC=C2c3ccccc3-c3ccccc32)cc1)C(=O)O.CCCOC(Cc1ccc(OCCCC=C2c3ccccc3-c3ccccc32)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.67
PPARA Q07869 16/20 0.67
PPARD Q03181 11/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736980 0.98 PPARG (0.70) PPARGPPARAPPARD
SCHEMBL6740660 0.98 PPARG (0.70) PPARGPPARAPPARD
SCHEMBL6740427 0.96 PPARG (0.67) PPARGPPARAPPARD
SCHEMBL6737662 0.95 PPARG (0.66) PPARGPPARAPPARD
SCHEMBL6731310 0.95 PPARG (0.66) PPARGPPARAPPARD
SCHEMBL6739053 0.94 PPARG (0.70) PPARGPPARAPPARD
SCHEMBL6740418 0.93 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL6731111 0.92 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL6731219 0.92 PPARA (0.80) PPARGPPARAPPARD
SCHEMBL6735222 0.91 PPARG (0.67) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123267-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP disclosed
WO-2000023415-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO disclosed