Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | FGF1 | P05230 | 2/20 | 0.41 |
| ▸ | FGF2 | P09038 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 6/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25362771 | 0.90 | SSTR1 (0.54) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL7152150 | 0.90 | SSTR1 (0.54) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL26836008 | 0.90 | SSTR1 (0.54) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL18573699 | 0.90 | SSTR1 (0.54) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL20107395 | 0.90 | SSTR1 (0.54) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL14413414 | 0.90 | PDPK1 (0.50) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL24378475 | 0.90 | PDPK1 (0.50) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL18573748 | 0.90 | PDPK1 (0.50) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL24378580 | 0.90 | PDPK1 (0.50) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL6878426 | 0.89 | SSTR1 (0.52) | PDPK1MTORSSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837867-B1 | MODIFIED ALPHA-D-Glcp-(1-2)-ALPHA-D-Glcp-(1-3)-ALPHA-D-Glcp-ANALOGUES | ALBERTA RES COUNCIL (CA) | 2001-08-16 | — | — | EP | disclosed |
| US-5929037-A | GLUCOSIDASE I INHIBITORS | ALBERTA RESEARCH COUNCIL (CA) | 1999-07-27 | — | — | US | disclosed |
| EP-0837867-A1 | MODIFIED $g(a)-D-Glcp-(1-2)-$g(a)-D-Glcp-(1-3)-$g(a)-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996040700-A1 | MODIFIED α-D-Glcp-(1-2)-α-D-Glcp-(1-3)-α-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1996-12-19 | — | — | WO | disclosed |