Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.71 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | LTA4H | P09960 | 4/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151232 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9154663 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL2204178 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9154372 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9150611 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL14267492 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9150185 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9153965 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9155028 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H | |
| SCHEMBL9150747 | 1.00 | RARB (0.71) | RARBNR5A1CYP3A4CYP2D6LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782995-B1 | Optically active Bis-methyldioxan derivatives and their use for electro-optical displays | ROLIC AG (CH) | 2001-08-16 | — | — | EP | disclosed |
| US-6225479-B1 | LIQUID CRYSTALLINE MIXTURES; ELECTRO-OPTICAL DEVICES | ROLIC AG (CH) | 2001-05-01 | — | — | US | disclosed |
| EP-0782995-A2 | Optically active Bis-methyldioxan derivatives and their use for electro-optical displays | Rolic AG (CH) | 1997-07-09 | — | — | EP | disclosed |