SCHEMBL7775775

SCHEMBL7775775

CCCC1=N/C(=C/c2[nH]c(-c3ccc[nH]3)cc2OC)C=C1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7775529 1.00 EZH2 (0.34) EZH2
Undecylprodiginine SCHEMBL7571765 0.92 EZH2 (0.40) EZH2
SCHEMBL7516789 0.92 EZH2 (0.40) EZH2
SCHEMBL1388971 0.92 EZH2 (0.40) EZH2
SCHEMBL7513857 0.92 EZH2 (0.40) EZH2
SCHEMBL7513859 0.92 EZH2 (0.40) EZH2
SCHEMBL7519904 0.92 EZH2 (0.40) EZH2
SCHEMBL7571884 0.92 EZH2 (0.40) EZH2
SCHEMBL7519901 0.92 EZH2 (0.40) EZH2
Undecylprodiginine SCHEMBL7571762 0.92 EZH2 (0.40) EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825983-B1 PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES PHARMACIA & UPJOHN SPA (IT) 2001-08-29 EP claimed