Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | EYA2 | O00167 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858995 | 0.98 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL4285151 | 0.91 | CA1 (0.47) | TDP1EYA2APPACEBLM | |
| SCHEMBL8536277 | 0.88 | TDP1 (0.65) | TDP1EYA2APPACEBLM | |
| SCHEMBL21652502 | 0.87 | TDP1 (0.46) | TDP1EYA2APPACEBLM | |
| SCHEMBL21652455 | 0.87 | TDP1 (0.46) | TDP1EYA2APPACEBLM | |
| SCHEMBL21033509 | 0.85 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL22293743 | 0.84 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| SCHEMBL21652488 | 0.82 | TDP1 (0.41) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1836354 | 0.81 | TDP1 (0.64) | TDP1EYA2APPACEBLM | |
| SCHEMBL21539283 | 0.81 | TDP1 (0.56) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470247-B1 | REVERSED PHASE CHROMATOGRAPHIC PROCESS | MALLINCKRODT INC (US) | 1997-04-16 | — | — | EP | claimed |
| US-5204005-A | Decolorization, separation, purification of water-soluble nonionic contrast media compounds; removing nonionic impurities | MALLINCKRODT, INC. (US) | 1993-04-20 | — | — | US | claimed |
| EP-0907395-B1 | REVERSED PHASE CHROMATOGRAPHIC PROCESS | MALLINCKRODT MED IMAGING IE (IE) | 2001-11-07 | — | — | EP | disclosed |
| EP-0863782-B1 | REVERSED PHASE CHROMATOGRAPHIC PROCESS | MALLINCKRODT MED IMAGING IE (IE) | 2001-08-16 | — | — | EP | disclosed |
| US-4826673-A | Methods and compositions for enhancing magnetic resonance imaging | MALLINCKRODT, INC. (US) | 1989-05-02 | — | — | US | disclosed |