Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 9/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7774650 | 0.99 | CACNA1B (0.42) | CACNA1BRENKDM4EALDH1A1HTT | |
| SCHEMBL6363858 | 0.89 | CACNA1B (0.46) | CACNA1BALDH1A1PSMB9PSMB8PSMB10 | |
| SCHEMBL7772779 | 0.83 | CACNA1B (0.48) | CACNA1BPSMB9PSMB8PSMB5 | |
| SCHEMBL7768808 | 0.83 | CACNA1B (0.47) | CACNA1BCTSSPSMB9PSMB8PSMB5 | |
| SCHEMBL7110494 | 0.82 | CACNA1B (0.50) | CACNA1B | |
| SCHEMBL7768807 | 0.78 | CACNA1B (0.46) | CACNA1BKDM4EALDH1A1 | |
| SCHEMBL7110461 | 0.78 | CACNA1B (0.44) | CACNA1B | |
| SCHEMBL4842928 | 0.76 | CACNA1B (0.67) | CACNA1BKDM4EALDH1A1HTTCTSS | |
| SCHEMBL7105548 | 0.76 | HSD17B10 (0.39) | CACNA1BRENKDM4EALDH1A1PSMB9 | |
| SCHEMBL7109533 | 0.76 | CACNA1B (0.38) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |