Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772426 | 0.91 | PTGIR (0.54) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7779788 | 0.83 | PTGIR (0.45) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7777405 | 0.79 | PTGIR (0.56) | PTGIRPTGDRPTGER1PTGER3PTGDR2 | |
| SCHEMBL7778533 | 0.79 | PTGIR (0.67) | PTGIRPTGDRPTGER1PTGER3TBXAS1 | |
| SCHEMBL7777534 | 0.79 | PTGIR (0.60) | PTGIRPTGDRPTGER1PTGER3TBXAS1 | |
| SCHEMBL7777531 | 0.79 | PTGIR (0.60) | PTGIRPTGDRPTGER1PTGER3TBXAS1 | |
| SCHEMBL7778516 | 0.79 | PTGIR (0.60) | PTGIRPTGDRPTGER1PTGER3TBXAS1 | |
| SCHEMBL9017294 | 0.79 | PTGIR (0.49) | PTGIRPTGDRPTGER1PTGER3PTGDR2 | |
| SCHEMBL7779787 | 0.78 | PTGIR (1.00) | PTGIRPTGDRPTGER1PTGER3PTGDR2 | |
| SCHEMBL7778549 | 0.77 | PTGIR (0.56) | PTGIRPTGDRPTGER1PTGER3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |