SCHEMBL7777360

SCHEMBL7777360

Cl[Rh].c1ccc(Pc2ccccc2)cc1.c1ccc(Pc2ccccc2)cc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
TDP1 Q9NUW8 4/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
GLA P06280 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ALDH1A1 P00352 5/20 0.35
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
F2 P00734 1/20 0.32
PLG P00747 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CMA1 P23946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL4445625 0.93 TDP1 (0.44) TSHRTDP1CA1CA2CA9
Benzene SCHEMBL28943358 0.93 TDP1 (0.44) TSHRTDP1CA1CA2CA9
SCHEMBL49343 0.93 TDP1 (0.44) TSHRTDP1CA1CA2CA9
SCHEMBL31125768 0.90 TSHR (0.37) TSHRTDP1CA1CA2CA9
Ammonia Solution, Strong SCHEMBL23797888 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9
Hydrogen Sulfide SCHEMBL1157712 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9
SCHEMBL184292 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9
SCHEMBL21597050 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9
SCHEMBL21597051 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9
Methane SCHEMBL8857655 0.89 TDP1 (0.41) TSHRTDP1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140756-A2 SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2001-10-10 EP disclosed
WO-2000040532-A2 SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-07-13 WO disclosed