Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.74 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776692 | 0.90 | PTGIR (0.61) | PTGIRTBXAS1KDM4CCA1CA2 | |
| SCHEMBL9427087 | 0.87 | PTGIR (0.81) | PTGIRTBXAS1PTGDR2KDM4C | |
| SCHEMBL9048557 | 0.85 | PTGIR (1.00) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9046469 | 0.83 | PTGIR (0.89) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9046416 | 0.82 | PTGIR (0.70) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8858680 | 0.79 | PTGIR (0.67) | PTGIRTBXAS1PTGDR2PTGER1PTGER3 | |
| SCHEMBL9047479 | 0.78 | PTGIR (0.85) | PTGIRTBXAS1PTGDR2KDM4C | |
| SCHEMBL8858692 | 0.78 | PTGIR (0.65) | PTGIRTBXAS1PTGDR2PTGER1PTGER3 | |
| SCHEMBL8858688 | 0.78 | PTGIR (0.65) | PTGIRTBXAS1PTGDR2PTGER1PTGER3 | |
| SCHEMBL9050868 | 0.77 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |