SCHEMBL7777446

SCHEMBL7777446

CCCCCCCCCCC(=O)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
PLA2G4B P0C869 7/20 0.62
RARB P10826 3/20 0.59
KMT2A Q03164 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
PLA2G4A P47712 1/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
ESR1 P03372 1/20 0.54
HTT P42858 1/20 0.51
MEN1 O00255 1/20 0.50
SLC22A2 O15244 1/20 0.50
TMPRSS2 O15393 1/20 0.50
F2 P00734 1/20 0.50
F10 P00742 1/20 0.50
PLG P00747 1/20 0.50
F12 P00748 1/20 0.50
PLAU P00749 1/20 0.50
PLAT P00750 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397588 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL6940826 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL167685 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL7776497 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL8587464 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL622925 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL1615177 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL2255418 1.00 TP53 (0.64) TP53TSHRPLA2G4BRARBKMT2A
SCHEMBL5705967 0.98 TP53 (0.62) TP53TSHRPLA2G4BRARBKMT2A
Hydrochloric Acid SCHEMBL8861908 0.98 TP53 (0.62) TP53TSHRPLA2G4BRARBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807675-B1 Optically active compound, liquid crystal compositions containing the optically active compound, and liquid crystal display device MITSUBISHI GAS CHEMICAL CO (JP) 2001-08-22 EP disclosed
EP-0718274-B1 Two-rings-containing phenyl ester compound and anti-ferroelectric liquid crystal composition containing the same MITSUBISHI GAS CHEMICAL CO (JP) 2000-02-09 EP disclosed
US-6018070-A WHEN INCORPORATED AS A COMPONENT FOR AN ANTIFERROELECTRIC LIQUID CRYSTAL COMPOSITION THE NOVEL TWO-RING-CONTAINING COMPOUND INCREASES THE RESPONSE SPEED OF THE COMPOSITION IN A BROAD TEMPERATURE RANGE MITSUBISHI GAS CHEMICALS COMPANY, INC. (JP) 2000-01-25 US disclosed
US-5840209-A DRIVEN BY A VOLTAGE CARRIED OUT BY SWITCHING AMONG ONE ANTI-FERROELECTRIC STATE AND TWO FERRIELECTRIC STATES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-11-24 US disclosed
EP-0807675-A1 Optically active compound, liquid crystal compositions containing the optically active compound, and liquid crystal display device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-11-19 EP disclosed
US-5660762-A HIGH DISPLAY QUALITY IN BROAD TEMPERATURE RANGE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-08-26 US disclosed
EP-0718274-A1 Two-rings-containing phenyl ester compound and anti-ferroelectric liquid crystal composition containing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-06-26 EP disclosed
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed