Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 1.00 |
| ▸ | EPAS1 | Q99814 | 13/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342730 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220708 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220705 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220709 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL9385467 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| Mycalazal 14 SCHEMBL28220153 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL9385000 | 1.00 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL9387973 | 0.93 | HIF1A (0.86) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220715 | 0.92 | HIF1A (0.85) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220149 | 0.92 | HIF1A (0.85) | HIF1AEPAS1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909271-B1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN SPA (IT) | 2001-09-26 | — | — | EP | disclosed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | disclosed |
| US-6071947-A | IMMUNOSUPPRESSANT AND ANTIINFLAMMATORY AGENTS FOR TREATMENT OF TRANSPLANT REJECTION, AUTOIMMUNE OR RHEUMATIC DISORDERS, VIRAL DISEASES | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-06-06 | — | — | US | disclosed |
| EP-0909271-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-04-21 | — | — | EP | disclosed |
| US-5847127-A | Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| WO-1998040380-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |
| EP-0825983-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-03-04 | — | — | EP | disclosed |
| WO-1997030029-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-08-21 | — | — | WO | disclosed |