Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991045 | 0.88 | TP53 (0.48) | TP53MAPTTHRBTDP1POLB | |
| SCHEMBL6989439 | 0.86 | LPAR1 (0.48) | TP53MAPTTHRBTDP1POLB | |
| SCHEMBL7089304 | 0.79 | RAF1 (0.47) | TP53MAPTTHRBPOLBKDM4E | |
| SCHEMBL6991831 | 0.78 | TACR1 (0.39) | MAPTTDP1ALDH1A1TACR1 | |
| SCHEMBL6988032 | 0.78 | TACR1 (0.39) | MAPTTDP1ALDH1A1TACR1 | |
| SCHEMBL6988027 | 0.78 | TACR1 (0.39) | MAPTTDP1ALDH1A1TACR1 | |
| SCHEMBL6983809 | 0.74 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6988800 | 0.74 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6986953 | 0.72 | CNR1 (0.40) | MAPTPOLBALDH1A1LPAR1TACR1 | |
| SCHEMBL6986957 | 0.72 | CNR1 (0.40) | MAPTPOLBALDH1A1LPAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1145714-A1 | DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |