Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813862 | 0.84 | TDP1 (0.47) | SLC7A5TDP1TSHRDPP4DPP7 | |
| Threonine SCHEMBL28147765 | 0.76 | SLC7A5 (0.54) | SLC7A5TDP1DPP4DPP7PREP | |
| SCHEMBL12962497 | 0.76 | — | — | |
| SCHEMBL17706712 | 0.75 | DPP4 (0.43) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL29919566 | 0.74 | SLC7A5 (0.38) | SLC7A5TDP1DPP4DPP7PREP | |
| Bromide SCHEMBL9580831 | 0.74 | — | — | |
| SCHEMBL20903952 | 0.73 | — | — | |
| SCHEMBL4282536 | 0.73 | — | — | |
| SCHEMBL1017270 | 0.73 | — | — | |
| SCHEMBL23748424 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600062-B1 | POLYMER-BOUND PACLITAXEL DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-09-19 | — | — | EP | disclosed |
| US-5569720-A | WATER SOLUBLE; ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-10-29 | — | — | US | disclosed |
| US-5362831-A | Antitumor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-11-08 | — | — | US | disclosed |
| EP-0600062-A1 | POLYMER-BOUND PACLITAXEL DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1994-06-08 | — | — | EP | disclosed |
| WO-1994000156-A1 | POLYMER-BOUND PACLITAXEL DERIVATIVES | PHARMACIA CARLO ERBA S.R.L. (IT) | 1994-01-06 | — | — | WO | disclosed |
| CN-1079971-A | The D51-7059 of polymer-bound | FRAMITALIA CARLO ERBA S R L (IT) | 1993-12-29 | — | — | CN | disclosed |
| CN-1058598-A | NEW LINKER FOR BIOACTIVE AGENTS | ERBA CARLO SPA (IT) | 1992-02-12 | — | — | CN | disclosed |