Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343339 | 0.98 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1MAP3K7 | |
| SCHEMBL7339388 | 0.95 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7342198 | 0.93 | RXFP1 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7345510 | 0.92 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7338852 | 0.92 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7340232 | 0.91 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7339422 | 0.91 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7340542 | 0.91 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7338448 | 0.91 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 | |
| SCHEMBL7338552 | 0.91 | AVPR2 (0.36) | AVPR2AVPR1AAVPR1BSIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |