Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MPO | P05164 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | SDCBP | O00560 | 1/20 | 0.58 |
| ▸ | SDC2 | P34741 | 1/20 | 0.58 |
| ▸ | CTSC | P53634 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580346 | 1.00 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL9499905 | 1.00 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL1617917 | 1.00 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL7781160 | 1.00 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| Water SCHEMBL29655419 | 0.99 | KDM4E (0.68) | KDM4EMAPTMEN1LMNAMPO | |
| Water SCHEMBL7631043 | 0.99 | KDM4E (0.68) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL30051936 | 0.98 | KDM4E (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL30051359 | 0.94 | ACE (0.64) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL30052771 | 0.93 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL31454970 | 0.92 | KDM4E (0.60) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633267-B1 | Process for the preparation of alpha-amino acid amide for use in peptide synthesis | SOLVAY (BE) | 2001-09-26 | — | — | EP | disclosed |
| US-5506362-A | Process for the preparation of an α-amino acid amide | SOLVAY (SOCIETE ANONYME) (BE) | 1996-04-09 | — | — | US | disclosed |
| EP-0633267-A1 | Process for the preparation of an alpha-amino acid amide for use in peptide synthesis | SOLVAY (Société Anonyme) (BE) | 1995-01-11 | — | — | EP | disclosed |
| US-4087416-A | LUTEINIZING HORMONE RELEASING FACTOR ANTAGONISTS | PARKE, DAVIS & COMPANY (US) | 1978-05-02 | — | — | US | disclosed |