Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.76 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.76 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380562 | 1.00 | SRD5A2 (0.76) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL8588600 | 1.00 | SRD5A2 (0.76) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7778486 | 0.90 | SRD5A1 (0.80) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7376956 | 0.90 | SRD5A1 (0.80) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL8585430 | 0.90 | SRD5A1 (0.80) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL8588304 | 0.88 | SRD5A1 (0.90) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7379641 | 0.88 | SRD5A1 (0.83) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7771657 | 0.88 | SRD5A1 (0.83) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7384127 | 0.85 | SRD5A2 (0.69) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL7778948 | 0.85 | SRD5A2 (0.69) | SRD5A2SRD5A1ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862556-B1 | 17-ALKYL-7-SUBSTITUTED-4-AZA STEROID DERIVATIVES | MERCK & CO INC (US) | 2001-09-05 | — | — | EP | claimed |
| US-5763361-A | 17-alkyl-7-substituted-4-aza steroid derivatives as 5-α-reductase inhibitors | MERCK & CO., INC. (US) | 1998-06-09 | — | — | US | claimed |
| EP-0862556-B1 | 17-ALKYL-7-SUBSTITUTED-4-AZA STEROID DERIVATIVES | MERCK & CO INC (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5872126-A | ENZYME INHIBITORS FOR TREATMENT OF PREMATURE LABOR | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0862556-A4 | 17-ALKYL-7-SUBSTITUTED-4-AZA STEROID DERIVATIVES | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0862556-A1 | 17-ALKYL-7-SUBSTITUTED-4-AZA STEROID DERIVATIVES | Merck & Co., Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5763361-A | 17-alkyl-7-substituted-4-aza steroid derivatives as 5-α-reductase inhibitors | MERCK & CO., INC. (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1998009632-A1 | METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR | MERCK & CO., INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| WO-1997015558-A1 | 17-ALKYL-7-SUBSTITUTED-4-AZA STEROID DERIVATIVES | MERCK & CO., INC. (US) | 1997-05-01 | — | — | WO | disclosed |