⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430665 | 0.70 | — | — | |
| SCHEMBL21011941 | 0.69 | — | — | |
| SCHEMBL2754315 | 0.61 | — | — | |
| SCHEMBL1980084 | 0.61 | — | — | |
| SCHEMBL1434436 | 0.61 | — | — | |
| SCHEMBL22785766 | 0.61 | — | — | |
| SCHEMBL1434434 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL31350515 | 0.59 | — | — | |
| SCHEMBL8159738 | 0.57 | — | — | |
| SCHEMBL665551 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018163212-A1 | A PROCESS FOR THE PREPARATION OF UMECLIDINIUM BROMIDE AND INTERMEDIATES THEREOF | GBR LABORATORIES PVT. LTD (IN) | 2018-09-13 | — | — | WO | claimed |
| CN-108558860-B | Method for synthesizing umeclidinium bromide | 成都伊诺达博医药科技有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-108558860-A | A kind of new method of synthesis umeclidinium | 成都伊诺达博医药科技有限公司 | 2018-09-21 | — | — | CN | disclosed |
| WO-2018163212-A1 | A PROCESS FOR THE PREPARATION OF UMECLIDINIUM BROMIDE AND INTERMEDIATES THEREOF | GBR LABORATORIES PVT. LTD (IN) | 2018-09-13 | — | — | WO | disclosed |
| EP-0881215-B1 | PROCESS FOR THE PREPARATION OF 4-METHYLENEPIPERIDINES | KAKEN PHARMA CO LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054586-A | Process for the preparation of 4-methylenepiperidine | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0881215-A1 | PROCESS FOR THE PREPARATION OF 4-METHYLENEPIPERIDINES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |