Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83796 | 0.89 | MEN1 (0.80) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL3241580 | 0.89 | MEN1 (0.50) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL7782032 | 0.82 | MEN1 (0.46) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL5215733 | 0.81 | IDO1 (0.47) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL28642267 | 0.81 | IDO1 (0.47) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL13047673 | 0.80 | MEN1 (0.53) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL8746056 | 0.80 | MAOA (0.61) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL166370 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL22894334 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL4770520 | 0.80 | MEN1 (0.67) | MEN1KMT2ARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135377-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034254-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-06-15 | — | — | WO | disclosed |
| EP-0505198-B1 | A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same | SANYO CHEMICAL IND LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5424194-A | Chemiluminescence | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0505198-A1 | A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4891297-A | STORAGE STABILITY, HIGH COLOR DENSITY | FUJI PHOTO FILM CO.,LTD. (JP) | 1990-01-02 | — | — | US | disclosed |