Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779220 | 1.00 | GRIK1 (0.41) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL5597687 | 0.90 | TP53 (0.40) | GRIK1GRIA4GRIK3GRIK5TSHR | |
| SCHEMBL8051853 | 0.90 | TP53 (0.40) | GRIK1GRIA4GRIK3GRIK5TSHR | |
| SCHEMBL5597686 | 0.90 | TP53 (0.40) | GRIK1GRIA4GRIK3GRIK5TSHR | |
| SCHEMBL5611085 | 0.83 | GRIK1 (0.42) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL5611081 | 0.83 | GRIK1 (0.42) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL42601 | 0.79 | FFAR3 (0.53) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL101165 | 0.79 | FFAR3 (0.53) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL42603 | 0.79 | FFAR3 (0.53) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL27220816 | 0.78 | GRIK1 (0.56) | GRIK1GRIA4GRIK3GRIK5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892822-B1 | LIQUID CURABLE RESIN COMPOSITION | DSM NV (NL) | 2001-08-29 | — | — | EP | disclosed |
| US-6063888-A | POLYDIMETHYLSILOXANE COMPOUND WHICH HAS AT LEAST TWO URETHANE BONDS IN ONE MOLECULE, AN UNREACTIVE ORGANIC GROUP ON AT LEAST END, AND A RADICAL CURABLE ETHYLENICALLY UNSATURATED GROUP AT OTHER END; SHELF LIFE; OPTICAL FIBER COATINGS BUNDLES | DSM N.V. (NL) | 2000-05-16 | — | — | US | disclosed |
| EP-0892822-A1 | LIQUID CURABLE RESIN COMPOSITION | DSM N.V. (NL) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038035-A1 | LIQUID CURABLE RESIN COMPOSITION | DSM N.V. (NL) | 1997-10-16 | — | — | WO | disclosed |