Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234145 | 0.97 | — | — | |
| SCHEMBL27081329 | 0.94 | TSHR (0.31) | — | |
| Methylamine SCHEMBL4593623 | 0.94 | — | — | |
| Water SCHEMBL1116008 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL7655934 | 0.94 | — | — | |
| Bromide SCHEMBL8507110 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL7783195 | 0.94 | — | — | |
| Iodide SCHEMBL2581387 | 0.94 | — | — | |
| SCHEMBL3439739 | 0.90 | — | — | |
| SCHEMBL18030003 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634407-B1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6075142-A | CATALYTICALLY REACTING CYANURIC CHLORIDE AND AQUEOUS TRIBROMOPHENOLATE SOLUTION CONTAINING A REDUCING AGENT AND A PHASE TRANSFER CATALYST TO FORM TRIS/TRIBROMOPHENOXY/-S-TRAIZINE | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0735084-B1 | Flame retardant thermoplastic styrenic resin composition | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0941268-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0633253-B1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5907040-A | REACTION OF CYANURIC CHLORIDE WITH BROMOPHENOL AND TERT-AMINECATALYSTS | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1999-05-25 | — | — | US | disclosed |
| WO-1998022522-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| US-5696302-A | INTERMEDIATES FOR PRODUCING TRIS(TRIBROMOPHENOXY)-S-TRIAZINE | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0735084-A1 | Flame retardant thermoplastic styrenic resin composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5498714-A | FROM CYANURIC CHLORIDE AND TRIBROMOPHENOLATE, PHASE TRANSFER AGENT, REDUCING AGENT TO PREVENT POLYMERIZATION | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0699702-A2 | Reaction products of carbonyl compounds and dihydric phenols | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0634407-A1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0633253-A1 | Process for production of tris(tribromophenoxy)-s-triazine | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-4680370-A | Branched polycarbonate composition from tris(hydroxyaryl)phosphorus compound | THE DOW CHEMICAL COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4025489-A | REACTION WITH PHOSGENE TO FORM LOW MOLECULAR WEIGHT POLYMER | MOBAY CHEMICAL CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-4001183-A | 1,4-BIS(4',4'-DIHYDROXY-TRIPHENYL-METHYL)-BENZENE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |