SCHEMBL7781679

SCHEMBL7781679

[BaH2].c1ccc2c(c1)CNS2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 1/20 0.45
OXTR P30559 1/20 0.34
PNMT P11086 1/20 0.33
CD44 P16070 1/20 0.33
MAOB P27338 1/20 0.33
HTR2C P28335 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 2/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700011 0.98
SCHEMBL60305 0.98
SCHEMBL4579661 0.95 RYR2 (0.45) RYR2OXTRPNMTCD44MAOB
Water SCHEMBL28227861 0.95 RYR2 (0.45) RYR2OXTRPNMTCD44MAOB
SCHEMBL28993067 0.95 RYR2 (0.45) RYR2OXTRPNMTCD44MAOB
Methyl Alcohol SCHEMBL5345590 0.91 RYR2 (0.42) RYR2OXTRPNMTCD44MAOB
Pyridine SCHEMBL28928515 0.84 RYR2 (0.38) RYR2ALOX15HSD17B10TDP1TSHR
SCHEMBL18638474 0.80 CA12 (0.41) RYR2OXTRPNMTCD44MAOB
SCHEMBL220767 0.74 HTR2C (0.46) RYR2PNMTCD44MAOBHTR2C
SCHEMBL7164803 0.74 RYR2 (0.44) RYR2OXTRPNMTCD44MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1136591-A1 HYDROPHILIZING AGENT FOR METALLIC MATERIAL, HYDROPHILIZING FLUID, METHOD OF HYDROPHILIZING, METALLIC MATERIAL, AND HEAT EXCHANGER NIHON PARKERIZING CO., LTD. (JP) 2001-09-26 EP disclosed