Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573260 | 1.00 | TSHR (0.70) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL6536159 | 1.00 | TSHR (0.70) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL9453921 | 1.00 | TSHR (0.70) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL11667209 | 1.00 | TSHR (0.70) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL8637315 | 0.98 | TSHR (0.67) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL4662825 | 0.92 | TSHR (0.63) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL180289 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL5392962 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL11795597 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA | |
| SCHEMBL10834721 | 0.92 | TSHR (0.81) | TSHREPHX2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818452-B1 | Preparation of cis-isoambrettolides and their use as a fragrance | MANE V FILS SA (FR) | 2001-10-24 | — | — | EP | disclosed |
| US-5786321-A | Preparation of cis-isoambrettolidies and their use as a fragrance | V. MANE FILS S.A. (FR) | 1998-07-28 | — | — | US | disclosed |
| US-5726328-A | Preparation of cis-isoambrettolides and their use as a fragrance | V. MANE FILS S.A. (FR) | 1998-03-10 | — | — | US | disclosed |
| EP-0818452-A2 | Preparation of cis-isoambrettolides and their use as a fragrance | V. Mane Fils S.A. (FR) | 1998-01-14 | — | — | EP | disclosed |