SCHEMBL7782360

SCHEMBL7782360

CCC[C@H]1CO[C@H]([C@H]2CO[C@H](c3ccc(Cl)c(F)c3)OC2)OC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 9/20 0.33
SLC6A4 P31645 7/20 0.32
SLC6A3 Q01959 1/20 0.32
HTR7 P34969 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782361 1.00 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3HTR7
SCHEMBL7781378 0.93 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL7781376 0.93 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL13198689 0.92 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3
SCHEMBL7781438 0.92 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL7781442 0.92 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL7781576 0.89 HTR2A (0.32)
SCHEMBL7781577 0.89 HTR2A (0.32)
SCHEMBL7781653 0.86 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL7781649 0.86 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732330-B1 Di-1,3-dioxane derivatives useful as liquid crystals ROLIC AG (CH) 2001-09-12 EP disclosed
US-5667721-A Liquid crystalline di-1,3-dioxane derivatives ROLIC AG (CH) 1997-09-16 US disclosed
EP-0732330-A1 Di-1,3-dioxane derivatives useful as liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1996-09-18 EP disclosed