SCHEMBL7782840

SCHEMBL7782840

O=C(O)C(S)CCC(S)C(=O)O.[Au]

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.65
RNPEP Q9H4A4 3/20 0.56
TDP1 Q9NUW8 4/20 0.44
LMNA P02545 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 2/20 0.44
ABCB11 O95342 1/20 0.44
F2 P00734 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
CYP2C9 P11712 1/20 0.44
HIF1A Q16665 1/20 0.44
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931181 0.97 FOLH1 (0.68) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL3796923 0.97 FOLH1 (0.68) FOLH1RNPEPTDP1LMNAALDH1A1
Hydrochloric Acid SCHEMBL11561884 0.93 FOLH1 (0.65) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL11045979 0.93 FOLH1 (0.65) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL11132841 0.93 FOLH1 (0.65) FOLH1RNPEPTDP1LMNAALDH1A1
Potassium SCHEMBL11044250 0.93 FOLH1 (0.65) FOLH1RNPEPTDP1LMNAALDH1A1
Ammonia Solution, Strong SCHEMBL10936273 0.93 FOLH1 (0.65) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL11159608 0.84 RNPEP (0.76) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL5476409 0.84 RNPEP (0.68) FOLH1RNPEPTDP1LMNAALDH1A1
SCHEMBL1405522 0.83 RNPEP (0.61) FOLH1RNPEPTDP1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845505-B1 Spherical colour pigments, process for their preparation and their use DMC2 DEGUSSA METALS CATALYSTS (DE) 2001-10-04 EP disclosed
US-6074754-A MEAN PARTICLE DIAMETER OF LESS THAN 10 MUM, ON THE BASIS OF AN OXIDIC OR SILICATE SUBSTRATE MATERIAL WITH NOBLE METAL DISTRIBUTED EXTREMELY FINELY ON AND/OR IN THE PARTICLES. PREFERRED PIGMENTS ARE PURPLE-COLORED DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-06-13 US disclosed